ABSTRACT: Promoting the agricultural sustainable development is one of the core objectives of agricultural comprehensive development (ACD), and the core of agricultural sustainable development lies in enhancing agro-ecological efficiency (AEE). Based on inter-provincial panel data from 2003-2017, the AEE was measured by a unexpected super-efficient SBM model. From the perspective of investment scale and investment structure, the impact of investment scale in ACD on AEE was examined using a panel econometric model, then characterizing the investment structure by the proportion of government funds in the investment of ACD, examining the non-linear relationship between investment structure of ACD and AEE seeking a reasonable proportion of government expenditure. Finally, a spatial econometric model was constructed to test the spatial spillover effect of the scale and structure of investment in ACD on AEE. Results showed that: (i) AEE of China is on the rise overall, but the efficiency level is still low and there is large scope for improvement. (ii) Due to the inefficient use of funds and the lag in the transformation of agricultural benefits, the scale of investment in ACD has a significant negative impact on AEE in the current period. (iii) The impact of investment structure of ACD on AEE presents a significant “inverted N” relationship, and the optimal proportion of government fund investment structure is 76.71%. The reasonable structure of investment in ACD at different food functional areas shows differences. (iv) After considering the spatial effect, the impact of ACD remains robust, but the spatial spillover effect prolongs the time lag of this impact of investment scale and starts to have a positive impact in the 2nd year after the investment. Guarantee the investment scale in ACD, reduce financial redundancy, establish a cooperation mechanism between ACD and agricultural ecological protection in neighboring areas, and increase the introduction of private capital can achieve sustainable development of agricultural economy.

RESUMO: Promover o desenvolvimento agrícola sustentável é um dos objetivos centrais do desenvolvimento agrícola abrangente (ACD), e o núcleo do desenvolvimento agrícola sustentável está no aumento da eficiência agro-ecológica (AEE). Com base nos dados do painel interprovincial de 2003-2017, o AEE foi medido por um modelo SBM super-eficiente inesperado. Da perspectiva da escala de investimento e da estrutura de investimento, o impacto da escala de investimento da ACD na AEE foi examinado utilizando um modelo econométrico de painel, então caracterizado a estrutura de investimento pela proporção de fundos governamentais no investimento da ACD, examina a relação não linear entre a estrutura de investimento da ACD e da AEE para buscar uma proporção razoável dos gastos governamentais. Finalmente, um modelo econométrico espacial foi construído para testar o efeito de spillover espacial da escala e da estrutura de investimento da TDAA na AEE. Os resultados mostram isso: (i) O AEE da China está em ascensão em geral, mas o nível de eficiência ainda é baixo e há uma grande margem para melhorias. (ii) Devido ao uso ineficiente dos fundos e ao atraso na transformação dos benefícios agrícolas, a escala de investimento na TCAA tem um impacto negativo significativo na TCAA no período atual. (iii) O impacto da estrutura de investimento da DCA na AEE apresenta uma relação “N invertida” significativa, e a proporção ótima da estrutura de investimento dos fundos governamentais é de 76,71%. A estrutura razoável de investimento na TCA em diferentes áreas funcionais de alimentos mostra diferenças. (iv) Depois de considerar o efeito espacial, o impacto da TCA permanece robusto, mas o efeito de spillover espacial prolonga o tempo de atraso deste impacto da escala de investimento e começa a ter um impacto positivo no 2º ano após o investimento. Garantir a escala de investimento na TCA, reduzir a redundância financeira, estabelecer um mecanismo de cooperação entre a TCA e a proteção ecológica agrícola em áreas vizinhas e aumentar a introdução de capital privado pode alcançar o desenvolvimento sustentável da economia agrícola.

RESUMO Atualmente, muitos estudos prova que exercícios adequados podem promover a função imunológica do corpo humano em certa medida, mas os atletas precisam de muito treinamento esportivo de alta intensidade, e sua função imunológica diminui em vez de melhorar. A fim de controlar o declínio da função imunológica dos atletas após treinamento de alta intensidade, este estudo propôs a administração da cápsula Zhenqi Fuzheng para alcançar esse objetivo. Através de comparação experimental, foram detectados parâmetros como o teor de glóbulos brancos, imunoglobulina, linfócitos T, hemoglobina humana e tempo de exaustão do exercício após treinamento de alta intensidade. Os resultados mostraram que, em comparação com o grupo controle que tomou a cápsula Zhenqi Fuzheng, o peso daqueles que tinham tomado a cápsula de qifuzheng não se alterou, e o teor de glóbulos brancos, imunoglobulina, hemoglobina e o tempo de exercício aumentaram em certa medida. Os resultados mostraram que a cápsula Zhenqi Fuzheng poderia inibir a diminuição da função imunológica corporal após exercícios de alta intensidade, e acelerar a recuperação da função imunológica humana. Espera-se que este estudo possa aumentar a imunidade dos atletas e reduzir a dor dos atletas após treinamento alta intensidade para fornecer uma certa referência.

ABSTRACT At present, many studies have proved that proper exercise can promote the immune function of human body to a certain extent, but athletes need a lot of high-intensity sports training, and their immune function declines instead of improving. In order to control the decline of immune function of athletes after high-intensity training, this study propose the Zhenqi Fuzheng capsule to achieve this goal. Through experimental comparison, the parameters such as white blood cell content, immunoglobulin number, T lymphocyte, human hemoglobin content and exercise exhaustion time were detected after high-intensity training. The results showed that compared with the control group taking Zhenqi Fuzheng, the weight of those who had taken qifuzhengs capsule did not change, and the content of white blood cells, immunoglobulin, hemoglobin content and exercise time increased to a certain extent. The results showed that Zhenqi Fuzheng could inhibit the decrease of body immune function after high-intensity exercise, then accelerate the recovery of human immune function. This study is expected to enhance the immunity of sports athletes, and reduce athletes’ pain after high-intensity training.

RESUMEN Actualmente, muchos estudios prueban que ejercicios adecuados pueden promover la función inmunológica del cuerpo humano en cierta medida, pero los atletas precisan mucho entrenamiento deportivo de alta intensidad, y su función inmunológica disminuye en vez de mejorar. A fin de controlar la declinación de la función inmunológica de los atletas después del entrenamiento de alta intensidad, este estudio propuso la administración de la cápsula Zhenqi Fuzheng para alcanzar ese objetivo. Por medio de comparación experimental, fueron detectados parámetros como el tenor de glóbulos blancos, inmunoglobulina, linfocitos T, hemoglobina humana y tiempo de agotamiento del ejercicio después de entrenamiento de alta intensidad. Los resultados mostraron que, en comparación con el grupo control que tomó la cápsula Zhenqi Fuzheng, el peso de aquellos que habían tomado la cápsula de qifuzheng no se alteró, y el tenor de glóbulos blancos, inmunoglobulina, hemoglobina y el tiempo de ejercicio aumentaron en cierta medida. Los resultados mostraron que la cápsula Zhenqi Fuzheng podría inhibir la disminución de la función inmunológica corporal después de ejercicios de alta intensidad, y acelerar la recuperación de la función inmunológica humana. Se espera que este estudio pueda aumentar la inmunidad de los atletas y reducir el dolor después de entrenamiento de alta intensidad para proveer una cierta referencia.

Background: The alga Laminaria japonica is the most economically important brown seaweed cultured in China, which is used as food and aquatic animal feedstuff. However, the use of L. japonica as a feedstuff in Apostichopus japonicasfarming is not ideal because A. japonicas does not produce enough enzyme activity for degrading the large amount of algin present in L. japonica. In this study, semi solid fermentation of the L. japonica feedstuff employing a Bacillus strain as the microbe was used to as a mean to degrade the algin content in L. japonica feedstuff. Results: The Bacillus strain, Bacillus amyloliquefaciens WB1, was isolated by virtue of its ability to utilize sodium alginate as the sole carbon source. Eight factors affecting growth and algin-degrading capacity of WB1 were investigated. The results of Plackett-Burman design indicated that fermentation time, beef extract, and solvent to solid ratio were the significant parameters. Furthermore, the mutual interaction between the solvent to solid ratio and beef extract concentration was more significant than the other pairs of parameters on algin degradation. Optimal values obtained from Central-Composite Design were 113.94 h for fermentation time, 0.3% (w/v) beef extract and 44.87 (v/w) ratio of solvent to feedstuff. Under optimal conditions, 56.88% of the algin was degraded when a 50-fold scale-up fermentation was carried out, using a 5-L fermenter. Conclusions: This study provides an alternative and economical way to reduce the algin content in L. japonicathrough degradation by WB1, making it a promising potential source of feed for cultured L japonica.

Background An endophytic fungus lives within a healthy plant during certain stages of, or throughout, its life cycle. Endophytic fungi do not always cause plant disease, and they include fungi that yield different effects, including mutual benefit, and neutral and pathogenic effects. Endophytic fungi promote plant growth, improve the host plant's resistance to biotic and abiotic stresses, and can produce the same or similar biologically active substances as the host. Thus, endophytic fungal products have important implications in drug development. Result Among the numerous endophytic fungi, we identified two strains, L10Q37 and LQ2F02, that have anti-acetylcholinesterase activity, but the active compound was not huperzine A. The aim of this study was to investigate the anti-acetylcholinesterase activity of secondary metabolites isolated from the endophytic fungi of Huperzia serrata. Microbial cultivation and fermentation were used to obtain secondary metabolites. Active components were then extracted from the secondary metabolites, and their activities were tracked. Two compounds that were isolated from endophytic fungi of H. serrata were identified and had acetylcholine inhibitory activities. In conclusion, endophytic fungal strains were found in H. serrata that had the same anti-acetylcholinesterase activity. Conclusion We isolated 4 compounds from the endophytic fungus L10Q37, among them S1 and S3 are new compounds. 6 compounds were isolated from LQ2F02, all 6 compounds are new compounds. After tested anti acetylcholinesterase activity, S5 has the best activity. Other compounds' anti acetylcholinesterase activity was not better compared with huperzine A.

A series of unsaturated esters were prepared via condensation of sodium carboxylates and alkenyl halide under the condition of macroporous polystyrene grafted quarternary ammonium salt as recyclable phase transfer catalyst, NaI as co-catalyst, Cu powder as inhibitor and H2O as solvent. Under optimal conditions, products yields are 78.2~ 96.0%. The catalyst can be convenient recycled and reutilized for about five times without losing its activity obviously.